The Portnoy Research Lab,
School of Chemistry, Tel Aviv University

The focus of our group research is the development of new methodologies for selective organic transformations, with a particular emphasis on organocatalysis. The importance of selectivity in chemical processes is paramount, often surpassing that of the reaction rate, as it directly impacts efficiency and practicality. In this context, novel catalytic systems play a crucial role in enhancing the precision of chemical transformations by refining or altering their selectivity. These advancements can significantly shorten synthetic routes, reduce costs, and improve the accessibility of key compounds.

 

Our past studies focused on developing methods to enhance chemoselectivity and induce stereoselectivity using polymer-supported catalysts, primarily with dendritic linkers. In contrast, our current efforts center on achieving site- and stereoselectivity with homogeneous organocatalysts.